SIMULTANEOUS DETECTION OF RIG-1, MDA5, AND IFIT-1 EXPRESSION IS A CONVENIENT TOOL FOR EVALUATION OF THE INTERFERON-MEDIATED RESPONSE

Simultaneous Detection of RIG-1, MDA5, and IFIT-1 Expression Is a Convenient Tool for Evaluation of the Interferon-Mediated Response

In this study, we developed a novel, multiplex qPCR assay for simultaneous detection of RIG-1, MDA5, and IFIT-1 at the mRNA level.The assay was validated in A549 cells transfected with in vitro transcribed RNAs.Both exogenous RNA-GFP and self-amplifying (saRNA-GFP) induced significant expression of RIG-1, MDA5, IFIT-1, as well as type I and III int

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Television Format as Cultural Negotiation

Despite the growing number of publications on television formats, specific theorisations Flower Shadow Box With LED Light regarding formats and format adaptation, in particular, are still rare.In this article, I introduce a synthesizing approach for studying format appropriation.Drawing on format study, media industry research and structuration the

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Revisiting Database Indexing for Parallel and Accelerated Computing: A Comprehensive Study and Novel Approaches

While the importance of indexing strategies for optimizing query performance in database systems is widely acknowledged, the impact of rapidly evolving hardware architectures on indexing techniques has been an underexplored area.As modern computing systems increasingly leverage parallel processing capabilities, multi-core CPUs, and specialized hard

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Design and additive manufacturing of elastic metamaterials with 3D lever-type inertial amplification mechanisms for mitigation of low-frequency vibration

This paper proposes a three-dimensional lever-type inertial amplification metamaterial for the mitigation of low-frequency vibration.This metamaterial was developed as a small, stiff, and single-phase structure that can inhibit the transmission of vibration in a certain frequency range below 100 Hz.An analytical model was developed to derive analyt

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